A medical 2009 study found that all Tricyclic antidepressants and SSRI’s (drugs that affect Serotonin), were associated with an increased risk of stroke and higher death rates overall.
The question that I have is was the increase in stroke and heart disease due to the antidepressants or the fact that less Estrogen was used by women?
I do not think it is coincidental that as hormone use subsided dramatically in 2003, antidepressant sales soared, (in 1996 13 million American used antidepressants, increasing drastically to 164 million women in 2003).
Studies have shown that not using Estrogen in the 5th decade, was associated with higher rates of arterial disease later in life.
We all need a boost in our serotonin as we age- but drugs may not always the be the best answer. Estrogen is one of the most powerful Serotonin drivers in a woman’s body.
Arch Intern Med. 2009;169(22):2128-2139.